Single-Molecule Approaches Embrace Molecular Cohorts

نویسندگان

چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Single-Molecule Approaches Embrace Molecular Cohorts

Enormous mechanistic insight has been gained by studying the behavior of single molecules. The same approaches used to study proteins in isolation are now being leveraged to examine the changes in functional behavior that emerge when single molecules have company.

متن کامل

Correction to Molecular Approaches to Chromatography Using Single Molecule Spectroscopy

The authors note that reference 87 in the original published manuscript was incorrectly cited as published in 2011 and should be corrected as shown below. This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.

متن کامل

Molecular Approaches to Chromatography Using Single Molecule Spectroscopy

■ CONTENTS Principles of Single Molecule Spectroscopy and Instrumental Techniques 84 General Considerations and Sample Requirements 84 Confocal Microscopy 85 Total Internal Reflectance Fluorescence Wide Field Imaging and Analysis 86 Chromatography Methods Studied by Single Molecule Spectroscopy 87 Reverse Phase Liquid Chromatography 87 Silica Surfaces: Normal Phase Chromatography and Capillary ...

متن کامل

Molecular motors: Single-molecule mechanics

Novel techniques are revealing the movements and forces associated with single interactions of motor proteins, such as myosin and kinesin, and also of processive enzymes, such as RNA polymerase.

متن کامل

Single-molecule approaches to stochastic gene expression.

Both the transcription of mRNAs from genes and their subsequent translation into proteins are inherently stochastic biochemical events, and this randomness can lead to substantial cell-to-cell variability in mRNA and protein numbers in otherwise identical cells. Recently, a number of studies have greatly enhanced our understanding of stochastic processes in gene expression by utilizing new meth...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Cell

سال: 2013

ISSN: 0092-8674

DOI: 10.1016/j.cell.2013.07.012